Key Publications Mediator kinase plays a key role in transcriptional reprogrammingM. Chen et al. Proc. Natl. Acad. Sci. USA 114, 10208-10213 (2017) The outcome of therapy in several types of cancer is impacted by Mediator kinaseI. B. Roninson et al. Cells 8, 821 (2019) Inhibition of Mediator kinase suppresses adverse effects of chemotherapy on tumor growthD. C. Porter et al. Proc. Natl. Acad. Sci. USA 109, 13799-13804 (2012) Mediator kinase inhibition prevents the development of drug resistanceA. C. Sharko et al. Cells 10, 144 (2021) Mediator kinase inhibition suppresses the growth of breast cancer and improves hormone therapyM. S. McDermott et al. Oncotarget 8, 12558-12575 (2017) Mediator kinase inhibition suppresses metastatic growth of colon cancer in the liverJ. Liang et al. Cancer Res 78, 6594-6606 (2018) COPZ1 depletion selectively kills tumor cells, whether or not the cells are dividingM. Shtutman et al. Proc Natl. Acad. Sci, USA 108 12449-12454 (2011) Share this:TwitterFacebookLike this:Like Loading...
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